A thesis at the University of Karbala, College of Medicine, examined the measurement of the concentration of TGF-B1 and CHIT1 from the serum by (ELISA) method, and fasting blood glucose (FBG), cumulative sugar (HBA1C) and some biomarkers of kidney function and lipid profile were measured in all The participants included the thesis titled Evaluation of Ketotrioxidase and Transformation of Growth Factor Beta 1 as Biomarkers of Nephropathy in Type 2 Diabetes Patients, by Ahmed Abdel-Zahra Al-Noor. ) in patients with T2DM, which may be indicators for early diagnosis in diabetic nephropathy from type 2 diabetic patients, as the thesis discussed the increase in the concentration of both TGF-B1, CHIT1 and statistically significant significantly in patients with nephropathy (860.33). +.-151.70pg/m1) (44.74+.-2.10pg/m1) respectively compared with the group of type 2 diabetic patients (36.45+.-0.81pg/m1), (426.33+.-38.70pg/m1) on respectively, and compared with a group of healthy controls (32.98+.-1.02pg/m),(195.83+.-25.17pg/m1, respectively, both groups had nephropathy and disease The diabetic z has a value of p>0.001
