Toxoplasmosis has negative consequences during pregnancy, especially in the first trimester, and leads to congenital toxoplasmosis and can be asymptomatic or can cause influenza-like illness with low-grade fever, lymphadenopathy and fatigue without regular screening procedures Before birth, it remains undiagnosed and untreated
It included a master’s thesis entitled (A Study of the Levels of Some Cytokines in Aborted Women with Cat Disease) by the student (Boys Adel Muhammad Ali Kazem)
The study also aims at the role of cytokines during the immune pathway during infection, an increase or decrease in IL-10, 1-PDL may be associated with fetal abortion, which could have a critical role in the course of diseases during infection with toxoplasmosis and the resulting abortion
The persons registered in this current study were classified into groups of sick individuals, an aborted female infected with acute toxoplasmosis and aborted females without any infection. A total of 100 samples were collected after abortion from the Obstetrics and Gynecology Hospital in Karbala, and placental tissue samples were placed in a Formalin for immunohistochemistry technique and sample making from April 2019 to March 2020. Tests were carried out using immunohistochemistry technique for placental ratio of IL-10, 1-PDL, TGF-beta
On the other hand, the thesis discussed the result of the study that residency for females was not related to the presence or absence of toxoplasmosis (p>0.05), the age was significantly different among the group of patients (P<0.05) and the number of abortions was not significantly different among the group of patients (P). <0.05) Toxoplasmosis, 1-PDL and TGF and their relationship during infection was statistically significant (P<0.05). The results of 1-PDL and TGF1 could be a candidate as a biomarker for the pathological effect of Toxoplasma gondii during pregnancy.
مزيد من المعلومات عن screening
screening
