The Iraqi Board of Histopathology at the Pathology Branch of the Faculty of Medicine, Karbala University, discussed the role of immunohistochemical expression in colorectal cancer patients, as the thesis submitted by the researcher (Zahraa Ali Hussein) entitled “Immunohistochemical expression of sath2 in colorectal cancer and its association with tumor grade and stage in the city of Karbala”
The discussion committee consisted of
Prof. Dr. Haider Abdul Ridha Kahyous, Chair
Prof. Dr. Muhammad Fawzi Abdul Mahdi, member
Prof. Dr. Zainab Abdul Ridha Abdul Ridha Abdul member
Dr.. Nizar Jabbar Mutaib, Supervisor
The study aimed to
Evaluate the performance of SATB2 in the diagnosis of colorectal cancer.
Evaluate the correlation between dye intensity and tumor grade and stage.
The study found that SATB2 staining was positive in 73.8% of cases and negative in 26.2%. The dye was grade 3 positive in 93.75% of cases, grade 2 positive in 90.9%, and grade 1 positive in 50%. The study also found a significant correlation (p-value less than 0.05) between dye intensity and tumor grade and stage.
