A message from Karbala Medicine discusses the role of chemokine CXCL10 and virulence factors of Escherichia coli isolates in urinary tract infection

The master’s thesis in the Department of Medical Microbiology, College of Medicine, University of Karbala discussed the role of chemokine CXCL10 and virulence factors of Escherichia coli isolates, as the message submitted by the researcher (Alaq Ali Abdul Hussein Muhammad) included the title “The role of chemokine CXCL10 and virulence factors of Escherichia coli isolates in urinary tract infection”

The discussion committee consisted of:
Prof. Dr. Abeer Zahir Naji, Chairman
Prof. Dr. Haider Qasim Rahim, Member
Prof. Dr. Abdul Hussein Sahib Kazim, Member
Prof. Dr. Masar Riyadh Rashid, Supervisor
Prof. Dr. Mai Mohamed Ali Mohamed Supervisor

The study aimed to evaluate the level of the immune marker chemokine 10 in the urine of patients and healthy individuals, as well as isolate and diagnose Escherichia coli from the urine of people with urinary tract infection, as well as molecular diagnosis of some virulence factors (Pap, FimH, OmpT, KpsmII).

The study also found that the level of the immune marker chemokine 10 was high in patients compared to healthy individuals and can be considered a diagnostic indicator for urinary tract infection. Some bacterial isolates also showed types of antibiotic resistance (MDR, XDR).