A master’s thesis in the Medical Microbiology Branch at the College of Medicine, University of Karbala, discussed the role of the in vitro effect of caspofungin molecules on skin fungi. It included the thesis submitted by the researcher (Sura Hamid Muhammad), which was entitled “In vitro effect of caspofungin-silver nanoparticles on skin fungi.”
The discussion committee consisted of:
a. Dr.. Ali Jalil Ali Hadi as president
a. Dr.. Ali Tariq Abdel Hassan, member
a. Dr. Alaa Abbas Fadel, member
a. Dr.. Ali Abdul Hussein Sadiq, supervisor
the mom. Dr.. Atheer Hamed Odeh as supervisor
The study aimed to demonstrate the in vitro evaluation of the antifungal efficacy of modified caspofungin and silver nanoparticles against dermatophytes compared to commercial caspofungin and silver nanoparticles as a control group.
The study also found that caspofungin was successfully prepared in the form of nanoparticles with silver
Ag@Cas NPs and modified Ag@Cas NPs,
Ag@Cas NPs have more antifungal activities than silver nanoparticles (AgNPs), caspofungin, and modified Ag@Cas NPs.
Most isolates were sensitive to low concentrations of Ag@Cas NPs with low MIC.
