A message at the Faculty of Medicine, Karbala University, discussed the role of iron toxicity in patients suffering from neurological diseases such as Alzheimer’s and Parkinson’s, where the message was presented by the researcher (Zahra Naji Abdul Razzak), which was entitled “The study of iron toxicity, oxidative lipolysis and programmed cell death in Alzheimer’s and Parkinson’s patients “
The study aimed to reduce the high incidence of iron toxicity in people with mental health problems such as Alzheimer’s and Parkinson’s disease and concluded that forms of iron are associated with success in diagnosing neurodegenerative diseases. The defective symmetry of iron and its redox activity probably play a role in the neuropathology of Alzheimer’s disease and Parkinson’s disease .
The study also found Ferroptosis is a new type of cell death that has been discovered in recent years and is usually accompanied by a large amount of accumulation of iron and lipid peroxidation during the cell death process. The occurrence of ferrous furunculosis depends on iron. The causative agents of ferruginosis can directly or indirectly affect glutathione peroxidase through various pathways, which leads to a decrease in antioxidant capacity and the accumulation of lipid reactive oxygen species (ROS) in cells, which ultimately leads to oxidative cell death.
